Combinostics at AAIC 2022

July 31 – August 3, 2022  |  San Diego, CA
Booth 400

Did you miss our team at the 2022 Alzheimer’s Association International Conference® or want to discuss our products further? Schedule some time to learn more about our cNeuro® suite, including the cMRI™ and cDSI™ applications, industry-first Dementia Differential Analysis report, and new clinically focused cMRI reports for dementia, multiple sclerosis, traumatic brain injuries, and epilepsy. Our complete AI software solution supports entire patient care pathways of major neurological disorders, including early detection, differentiation of diagnosis, treatment planning, and monitoring.

Join presentations of our research at AAIC 2022.

Sunday, July 31

Automated detection of lacunar infarcts from MRI images

Presenter: Jyrki Lötjönen, CSO, Combinostics
Combinostics co-authors: Frederik Barkhof (Medical Advisor), Jin Gong (Imaging Scientist), Juha Koikkalainen (Senior Imaging Scientist)
Other authors represent the Helsinki University Hospital, University of Turku, University of Eastern Finland and Kuopio University Hospital, University of Perugia, Danish Dementia Research Centre, Alzheimer Centre Amsterdam, University College London, and Vrije Universiteit Amsterdam.

Association between 10-year cardiovascular mortality-risk and neuroimaging biomarkers in the FINGER trial

Presenter: Gazi Saadmaan Hossain, University of Eastern Finland

Combinostics co-author: Jyrki Lötjönen, CSO

Other authors represent the Karolinska Institutet, Imperial College London, Finnish Institute for Health and Welfare, Kuopio University Hospital, University of Turku, Turku University Hospital, University of Oulu, University of Helsinki, Oulu University Hospital, King Abdulaziz University, University of Eastern Finland, Kuopio University Hospital, and Karolinska University Hospital.

Optimizing cCOG, a web-based tool, to detect dementia with Lewy bodies

Presenter: Aniek M. van Gils, Alzheimer Centre Amsterdam

Combinostics co-authors: Antti Tolonen, Senior Imaging Scientist; Jyrki Lötjönen, CSO

Other authors represent the Vrije Universiteit Amsterdam.

Using a combination of science and innovative AI technology, we aim to make a difference in the lives of patients with neurological disorders.

Our cNeuro® suite puts the focus on patients by providing clinicians with objective, systematic insights for confident, evidence-based diagnostic and management decisions.

Patient data from multiple sources are integrated and compared with data from previous patients and healthy controls: demographic information, imaging (cMRI) and other biomarkers, clinical characteristics, and neuropsychology tests. 

Applications in the cNeuro® suite:

*WIP – not yet cleared for clinical use.
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Our AI-driven software tools support early detection, differential diagnosis, prediction of progression, and monitoring of neurodegenerative disorders.


cMRI provides fully automated brain MRI quantification for increased throughput, greater objectivity, and high-quality reporting for improved patient care.

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Dementia Differential Analysis report

The new Dementia Differential Analysis report is based on MRI data only, using our cDSI application’s proprietary machine learning method that measures the similarity of disease-specific imaging biomarker values from the patient to those from 2,000+ patients with a confirmed neurodegenerative disease:

Clinically focused cMRI reports

Our new clinically focused cMRI reports facilitate patient management as well as communication between radiologists, neurologists, patients, and their caregivers. These include reports for: